Show simple item record

Chapter 15 Brain Tumors and the Lynch Syndrome

dc.contributor.authorPeltomäki, Päivi
dc.contributor.authorGylling, Annette
dc.date.accessioned2019-10-04 14:27:25
dc.date.accessioned2020-04-01T14:07:02Z
dc.date.accessioned2016-08-01 23:55
dc.date.accessioned2019-10-04 14:27:25
dc.date.accessioned2020-04-01T14:07:02Z
dc.date.accessioned2016-12-31 23:55:55
dc.date.accessioned2019-10-04 14:27:25
dc.date.accessioned2020-04-01T14:07:02Z
dc.date.available2020-04-01T14:07:02Z
dc.date.issued2011
dc.identifier612584
dc.identifierOCN: 1030821093en_US
dc.identifier.urihttp://0-library-oapen-org.catalogue.libraries.london.ac.uk/handle/20.500.12657/32348
dc.description.abstractLynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003).
dc.languageEnglish
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PD Science: general issuesen_US
dc.subject.otherbrain tumors
dc.subject.otherlynch syndrome
dc.subject.otherbrain tumors
dc.subject.otherlynch syndrome
dc.subject.otherColorectal cancer
dc.subject.otherDNA methylation
dc.subject.otherDNA mismatch repair
dc.subject.otherGene
dc.subject.otherGlioblastoma
dc.subject.otherGlioma
dc.subject.otherHereditary nonpolyposis colorectal cancer
dc.subject.otherMutation
dc.subject.otherNeoplasm
dc.titleChapter 15 Brain Tumors and the Lynch Syndrome
dc.typechapter
oapen.identifier.doi10.5772/21293
oapen.relation.isPublishedBy09f6769d-48ed-467d-b150-4cf2680656a1
oapen.relation.isPartOfBooke4114cfa-bb48-49d8-9a08-d0338a9a7b48
oapen.relation.isFundedBy7292b17b-f01a-4016-94d3-d7fb5ef9fb79
oapen.collectionEuropean Research Council (ERC)
oapen.chapternumber1
oapen.grant.number232635
oapen.grant.acronymEPISUSCEPTIBILITY
oapen.grant.programFP7
oapen.remark.publicRelevant Wikipedia pages: Brain tumor - https://en.wikipedia.org/wiki/Brain_tumor; Colorectal cancer - https://en.wikipedia.org/wiki/Colorectal_cancer; DNA methylation - https://en.wikipedia.org/wiki/DNA_methylation; DNA mismatch repair - https://en.wikipedia.org/wiki/DNA_mismatch_repair; Gene - https://en.wikipedia.org/wiki/Gene; Glioblastoma - https://en.wikipedia.org/wiki/Glioblastoma; Glioma - https://en.wikipedia.org/wiki/Glioma; Hereditary nonpolyposis colorectal cancer - https://en.wikipedia.org/wiki/Hereditary_nonpolyposis_colorectal_cancer; Mutation - https://en.wikipedia.org/wiki/Mutation; Neoplasm - https://en.wikipedia.org/wiki/Neoplasm
oapen.identifier.ocn1030821093


Files in this item

Thumbnail
Name:
612584.pdf
Size:
865.2Kb
Format:
PDF
License:
https://creativecommons.org/li ...
View/Open

This item appears in the following Collection(s)

Show simple item record